| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2275f0617e27b13ded0ae6788517ff4d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
| filingDate |
2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4abcdb8315fde916daa89baeb943ece6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eedfa31ff350762670591fde83458698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_288f8c11d67188779020ed8c93372976
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca395d76789e9bf231251283cfdc6996
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63f83ccc7bc750717f19fd4b571e4418 |
| publicationDate |
2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114377014-A |
| titleOfInvention |
Use of DNA topoisomerase I inhibitor and Akt inhibitor in combination for the preparation of anti-colorectal cancer drugs |
| abstract |
The invention discloses the use of a DNA topoisomerase I inhibitor and an Akt inhibitor in combination for preparing an anti-colorectal cancer drug. The present invention finds that the DNA topoisomerase I inhibitor irinotecan and the Akt inhibitor MK-2206 have the activity of synergistically inhibiting the proliferation of colorectal cancer cells, and the combination of these two inhibitors can be developed into a drug for the treatment of colorectal cancer Prospects. |
| priorityDate |
2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |