| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3b66e1dc31e9503adac1170aa307f0c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5418 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd7222df5471d0945b98b558b49f014d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_498b80a7ae7adc1b00b4c37b8a7f1d5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c249d73334550c34de481cdf9271c6d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e08a3cf4e021f3697933f787cce363f5 |
| publicationDate |
2022-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114369167-A |
| titleOfInvention |
Bifunctional fusion protein composed of anti-PD-L1 antibody and IL-7 |
| abstract |
The invention provides a bifunctional fusion protein consisting of an anti-PD-L1 antibody and IL-7; specifically, the present invention provides a recombinant bifunctional fusion protein comprising: a first structural unit (D1); and a second structural unit (D2); wherein the first building block is an antibody that specifically binds to PD-L1 protein; the second structural unit comprises IL-7, the fusion protein can enrich IL-7 cell factors in a tumor microenvironment, specifically activates an immune system in the tumor microenvironment, and can greatly reduce toxic and side effects. |
| priorityDate |
2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |