http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114349704-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd37b53f7a639daf413b490204ba4613 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 |
| filingDate | 2022-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_963fcc110f29749e0031a7fcc740b81e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbc75c4e28bbbc80c0dff73f8e24818a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_807b8fcda271a55c286faeb0fe5fbea9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ef28439fed05849a26ea719ad2901b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45bfd23f1c19bc6d3d0f0a45369fe95 |
| publicationDate | 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114349704-A |
| titleOfInvention | Trifluoromethyl conjugated pyrazole spiro cyclopropane compound and synthesis method thereof |
| abstract | The invention discloses trifluoromethyl conjugated pyrazole spiro propane compounds and a synthesis method thereof, belonging to the technical field of organic synthesis. Mixing substituted methylene cyclopropane 1, 1-substituted pyrazolidone compounds 2, inorganic base, copper salt or silver salt additive and trifluoroethanol 3, and heating to react to prepare trifluoromethyl conjugated pyrazole spiro cyclopropane compounds 4; the synthesis method is efficiently completed through one-pot series reaction among substituted methylene cyclopropane, 1-substituted pyrazolidone and trifluoroethanol, the whole process has high atom economy, mild reaction conditions and simple and efficient process; meanwhile, the method has the advantages of wide substrate range, good functional group tolerance and the like. |
| priorityDate | 2022-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.