http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114344483-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08f13af9eed1607b6583a1306d9a1294 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 |
| filingDate | 2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5746c5bbc902453adf87c249aa165e41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f893be779e3a25eb0292e61336e71daf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f25194e0784b489b760a2c14e622d239 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43d910edc494336c9be65a70bb168499 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2406cf7e698d4a442d75afcc623b1b4c |
| publicationDate | 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114344483-A |
| titleOfInvention | Integrated targeted nanomedicine for lung cancer diagnosis and treatment based on ultra-small molecule H-dot nano-drug delivery system and its preparation method |
| abstract | The invention discloses a targeted nano-drug (Gef/H-dot) integrated in the diagnosis and treatment of lung cancer based on an ultra-small molecule H-dot nano-drug loading system and a preparation method thereof, belonging to the technical field of targeted nano-drugs. The preparation method comprises the following steps: The following steps: convert β-CD into Ald-CD, combine Ald-CD with EPL to form CDPL, combine CDPL with a near-infrared (NIR) fluorophore, and then succinylate to obtain NIR fluorophore-CDPL ± , It is named H-dot, and H-dot is compounded with Gef-targeted drug to obtain Gef/H-dot; it is an ideal multifunctional nano-drug, which is used for real-time NIR fluorescence image-guided staging detection and surgical intervention. It has unlimited potential in terms of pathological assistance and targeted delivery of antitumor drugs (Gef) to achieve efficient targeted therapy and reduce treatment-related adverse reactions. |
| priorityDate | 2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.