http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114344264-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3194bff3c9c57ec256e9cf63c11aea6 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 |
filingDate | 2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2ab03155728ccee6d8f7090b6a32e98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f04c2fde80aabe1838010369e3be04a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06a316e6d62617a22934e70cbe6c4419 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_780b23b354ba9428cd68b020f11f5a16 |
publicationDate | 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114344264-A |
titleOfInvention | A kind of budesonide nasal spray and preparation method thereof |
abstract | The invention provides a budesonide nasal spray and a preparation method thereof. The preparation method of the budesonide nasal spray of the present invention comprises the following steps: S1. Dissolving the auxiliary material in water to obtain the auxiliary material solution; S2. Dispersing the compound Avicel of microcrystalline cellulose and sodium carboxymethyl cellulose in water and adding Carry out the first shearing to obtain Avicel suspension, the rotating speed of the first shearing is 4000rpm-9000rpm, and the shearing time is 10min-30min; S3. The surfactant is dissolved in water, and the micronized Budesonide, followed by dispersion to obtain Budesonide Suspension I; S4. Add the auxiliary material solution and Budesonide Suspension I to the Avicel suspension in turn, add water to determine the weight to 100%, and carry out the second time Sheared to obtain Budesonide Suspension II, from which Budesonide Nasal Spray was prepared. |
priorityDate | 2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.