| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb60c37092e5304c33e022618163f534 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2020-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38459a0f08e0275815d9793e8d9bc93c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06ebe6b87ed35dccb2f9a56849585548
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb5dfb07e9099f39159c5ebf59b61b14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2930f4a06fc7ef508067a6f85b1e760
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd9d1883d7d5e2ea51d72eb9666f7cbf |
| publicationDate |
2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114341193-A |
| titleOfInvention |
Chimeric Cytokine Receptor Comprising a TGFB Binding Domain |
| abstract |
Provided herein are chimeric cytokine receptors having binding domains capable of binding to TGF-beta ligands or TGF-beta receptor antibodies. Such receptors constitutively and/or via TGF-beta ligands or TGF-beta receptors when present on immune cells (CAR-T cells) with chimeric antigen receptors (CARs) Binding of antibodies to increase CAR-T cell expansion, activity and persistence. The present invention also provides methods of making and using the chimeric cytokine receptors described herein. |
| priorityDate |
2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |