http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114324870-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf80d252c03a54eff79c66678fdee30a |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b264e8ee341233c04c4f70f17596084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8333bb1e0e9e5375b707c18209ba35fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f910780bbccc09f2ac2a1c285a341db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4fcdc6dcc53f9c453f7de9d3c8ac3cb |
publicationDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114324870-A |
titleOfInvention | Lung cancer biomarker targeting myeloid cell lactic acid transport signal and detection kit |
abstract | The invention discloses a lung cancer biomarker and a detection kit for a target medullary cell lactic acid transport signal, and belongs to the technical field of biological medicines. The research results of the invention prove that MCT 2-mediated lactic acid transport redefines the differentiation and development direction of M-MDSC for the first time, thereby accelerating the growth of tumor in TME. Targeting lactate metabolism and transport signals in myeloid cells may be a potential therapeutic option for clinical lung cancer, while lactate transport signal levels in myeloid cells may also serve as biomarkers for early diagnosis and prognosis of lung cancer. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115267187-A |
priorityDate | 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.