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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf80d252c03a54eff79c66678fdee30a
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
filingDate 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b264e8ee341233c04c4f70f17596084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8333bb1e0e9e5375b707c18209ba35fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f910780bbccc09f2ac2a1c285a341db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4fcdc6dcc53f9c453f7de9d3c8ac3cb
publicationDate 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114324870-A
titleOfInvention Lung cancer biomarker targeting myeloid cell lactic acid transport signal and detection kit
abstract The invention discloses a lung cancer biomarker and a detection kit for a target medullary cell lactic acid transport signal, and belongs to the technical field of biological medicines. The research results of the invention prove that MCT 2-mediated lactic acid transport redefines the differentiation and development direction of M-MDSC for the first time, thereby accelerating the growth of tumor in TME. Targeting lactate metabolism and transport signals in myeloid cells may be a potential therapeutic option for clinical lung cancer, while lactate transport signal levels in myeloid cells may also serve as biomarkers for early diagnosis and prognosis of lung cancer.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115267187-A
priorityDate 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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