http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114316026-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63e4214a51eddd1e5503c58e66237531 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 |
| filingDate | 2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d42d6c57b10c587959fca33dd032dda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_205ff3ad8e64ead50fda6bd13c4292a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96b80ae882cdddc8637deb9733e1cc77 |
| publicationDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114316026-A |
| titleOfInvention | A kind of IL17RA and/or IL17RC gene humanized non-human animal and its construction method and application |
| abstract | The present invention provides a non-human animal with humanized IL17RA and/or IL17RC gene and a construction method thereof, a humanized IL17RA and/or IL17RC protein, a humanized IL17RA and/or IL17RC gene, a humanized IL17RA and/or IL17RC gene, a The targeting vector of IL17RA and/or IL17RC gene and its application in the field of biomedicine, the nucleotide sequence encoding human IL17RA and/or IL17RC protein is introduced into the genome of a non-human animal by means of homologous recombination, and the animal can Normal expression of human or humanized IL17RA and/or IL17RC protein can be used as an animal model for human IL17RA and/or IL17RC signaling mechanism research, orthopedic disease, metabolic disease, inflammation, tumor or autoimmune disease drug screening. The research and development of new drugs has important application value. |
| priorityDate | 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 863.