http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114315698-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9105b429db179079920b4c61ee004cd3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-76 |
| filingDate | 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c9ebc3b7067b02d57fa201ec1afafa6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e98c11c47e69ed8b7cf886f8fff640f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09797d5f22fa243ed5f38b8eca76b051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4798184058ab82e64464c9888ee36d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce2530054b8b5a35ca4b792c868d08d0 |
| publicationDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114315698-A |
| titleOfInvention | C5a blocker Avacopan chiral impurity and synthetic method thereof |
| abstract | The present invention provides a novel Avacopan chiral impurity (Avacopan analogue). The Avacopan analogue is prepared by taking the compound of the formula III as an initial raw material and performing chiral reduction on the compound of the formula III to prepare the compound of the formula I and coupling the compound of the formula I and the compound of the formula II. The invention also provides the application of the Avacopan analogue as an impurity reference substance of Avacopan, which can effectively reduce the content of corresponding impurities in Avacopan on one hand, and can reduce the toxic and side effects of the corresponding impurities on the other hand, thereby having important significance. |
| priorityDate | 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.