http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114288250-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d65c117572e111528218bfbf5eef598f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 |
| filingDate | 2022-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b91c9e41fd8df5105f4df0f4416dc360 |
| publicationDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114288250-A |
| titleOfInvention | A kind of adipocyte-targeted transmembrane transport liposome drug carrier and preparation method and use thereof |
| abstract | The invention provides a high-efficiency adipocyte-targeted transmembrane transport liposome drug carrier and a preparation method and application thereof. The present invention combines the liposome modified with hyaluronic acid and the liposome modified with adipocyte targeting peptide for the first time, and the two modification methods synergistically improve the targeting effect of the liposome drug carrier on the adipocyte. The present invention improves the encapsulation efficiency of liposomes for macromolecular proteins and nucleic acids by means of cationic lipid molecules modified by oligolysine for the first time, and can realize targeted entry of proteins, nucleic acids and the like into adipocytes. |
| priorityDate | 2022-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.