http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114288249-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c732ed7dd030239e2e90538d54b1d8d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
| filingDate | 2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a95fdf9cce6ecba56a2281de7deccdc |
| publicationDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114288249-A |
| titleOfInvention | A nanometer immunomodulatory drug for regulating the ratio of Treg/Th17 cells in the lesion microenvironment and its preparation method and application |
| abstract | The invention discloses a nanometer immunoregulatory drug for regulating the ratio of Treg/Th17 cells in the microenvironment of a lesion, and a preparation method and application thereof. The lipid bimolecular membrane modified by PEG-PEG is used as the outer shell, and the drug carrier modified with antibody-specific and highly expressed markers on the surface of important placental immunoregulatory cells Treg cells and Th17 cells is used as the inner core, and the drug carrier is loaded with superparamagnetic magnetism. Ferric oxide SPIO nanoparticles, small molecule drugs regulating placental Treg cell and Th17 cell function, therapeutic genes or combinations thereof. The nano-immune regulating drug for regulating the ratio of Treg/Th17 cells in the microenvironment of the lesion can effectively avoid the absorption of non-specific drugs by other organs outside the maternal placenta and the fetus, thereby realizing the delivery and function regulation of specific drugs for Treg cells and Th17 cells in the placenta. . |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115068503-A |
| priorityDate | 2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.