| abstract |
The invention relates to a polymer micelle oral liquid containing gabapentin complex, wherein the gabapentin complex is prepared from gabapentin and fatty acid or from gabapentin, fatty acid salt and hydrochloric acid, and the polymer material is polyvinyl caprolactam-polyvinyl acetate ‑Polyethylene glycol graft copolymer. The prepared polymer micelle oral liquid containing gabapentin complex can effectively reduce the formation of gabapentin intramolecular condensate lactam, improve drug stability, mask the bitter taste of gabapentin, and improve patient compliance. |