http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114277017-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
| filingDate | 2022-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114277017-B |
| titleOfInvention | Novel feedback inhibition resistant hyaluronic acid fusion enzyme, preparation method and enzyme digestion process thereof |
| abstract | The invention discloses a novel hyaluronic acid fusion enzyme with feedback inhibition resistance, a preparation method and an enzyme digestion process thereof. The hyaluronic acid binding protein and the leech hyaluronic acid hydrolase are connected through a Linker formed by 9 repeated amino acid sequences of glycine and serine, and 6 histidine sequences are fused as tags. The hyaluronic acid binding protein part of the novel hyaluronic acid fusion enzyme can be specifically bound with substrate hyaluronic acid, so that the novel hyaluronic acid fusion enzyme is beneficial to the function exertion of a hyaluronic acid hydrolase part, solves the problem of feedback inhibition in a hyaluronidase catalytic reaction, obviously improves the enzyme digestion efficiency, and has good industrial production value and economic value. |
| priorityDate | 2022-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.