http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114272430-A

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filingDate 2022-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_931fe832ed38a939e4b184becf23b0cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98570396d0461e9306b1d6ed10c2f72d
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publicationDate 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114272430-A
titleOfInvention A kind of thermosensitive embolic microsphere and preparation method thereof
abstract The embodiments of the present application provide a temperature-sensitive embolic microsphere and a preparation method thereof, which relate to the field of medical devices. The temperature-sensitive embolic microspheres are mainly cross-linked structures formed by cross-linking and polymerizing water-soluble macromolecules and the first cross-linking agent, and are formed by cross-linking and polymerizing with water-soluble monomers, temperature-sensitive molecules and the second cross-linking agent. The three-dimensional network structure formed by the cross-linked structures intersecting and intertwining with each other. The preparation method of temperature-sensitive embolization microspheres is to add the water-phase system mainly prepared by water-soluble polymer, water-soluble monomer, temperature-sensitive molecule and cross-linking agent into the oil-phase system to form water-in-oil the reversed-phase suspension polymerization system; make the reversed-phase suspension polymerization system carry out cross-linking polymerization reaction. The embolic microspheres of the embodiments of the present application are easy to produce and have temperature sensitivity; the embolic microspheres of a certain specification range shrink in size when the temperature increases, and the particle size distribution narrows, so that they can be accurately matched with the size of the patient's blood vessels .
priorityDate 2022-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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