http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114272255-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_198ef01a1dcd1216fe730d49fd423061 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate | 2020-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ab4d1c589f4bcdbea5b09b8aac7113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d370d47e9385f6ee73006d27b3645783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b04b59ee553f37e6e51a32a1f6884c9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5300de1da4aee13d20b1c99322c3f32d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6741c0b5488f93567824f141fc91f733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c34d0bf32a784c45470b9d49176a2c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0743d38b1638a48c9b09309d8e0c8b7e |
publicationDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114272255-A |
titleOfInvention | Use of ginseng flavonoid glycosides in the preparation of angiogenesis-promoting drugs |
abstract | The invention relates to the technical field of medicine, and relates to a new use of ginseng flavonoid glycosides in pharmacy, in particular to the use of ginseng flavonoid glycosides alone or as an active ingredient in the preparation of drugs for treating acute or chronic diseases accompanied by insufficient angiogenesis, or for promoting angiogenesis. use. The invention adopts VEGF receptor inhibitor to induce zebrafish angiogenesis deficiency model and human vein endothelial cell injury model, simulates the pathological state of disease angiogenesis deficiency, studies the effect of ginseng flavonoid glycosides in promoting angiogenesis, and finds that ginseng flavonoid glycosides promote blood vessel formation The neonatal effect is obvious, and the effective rate is more than 90%, and its mechanism of action is related to the expression of VEGF receptor and apoptosis. It shows that ginseng flavonoid glycosides have effective angiogenesis-promoting effect, and are suitable for treating diseases related to insufficient angiogenesis. It has a wide range of sources and low toxicity, provides a new way for the treatment of diseases with insufficient angiogenesis, and is a potential preparation of angiogenesis drugs. |
priorityDate | 2020-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.