http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114272209-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73949801489c068ddec9040791f4aa27 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 |
| filingDate | 2021-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d68be095a0a9cd574bf871814dd8b371 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32a78d3546dccc4b4c1502fb9f5c1aee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e749d83b421e685b5302d2b56062058b |
| publicationDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114272209-A |
| titleOfInvention | A kind of nano-lipid microsphere of chemical anti-tumor drug, and the combined application of the nano-lipid microsphere and tumor immunotherapy drug |
| abstract | The invention constructs: nano-lipid microspheres of anti-tumor chemical drugs that can selectively release drugs at tumor sites; and combining the nano-lipid microspheres with tumor immunotherapy drugs, such as anti-PD-1 monoclonal antibody (αPD- 1) Combined application in the treatment of malignant tumors. According to the analysis of the onset time of the above-mentioned nano-lipid microspheres and tumor immunotherapy drugs in vivo, the present invention designs three kinds of combined treatment schemes, including the simultaneous injection of the above-mentioned nano-lipid microspheres and tumor immunotherapy drugs, and the first injection The above nanolipid microspheres are injected with tumor immunotherapy drugs after two days, and the tumor immunotherapy drugs are injected first, and the nanolipid microspheres are injected after two days. Through the above combined application, the step of pre-administering hormones in the case of using anti-tumor chemical drugs alone can be omitted, and immunotherapy can be sensitized to achieve the synergistic effect of tumor chemotherapy and immunotherapy. |
| priorityDate | 2021-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.