http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114262609-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13da9ccd5a08e36c49b34a872c6743d8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2020-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29853a6a7b3d43e8dcd5da5c9fe7edb7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f930850a6943ab131af09edd8effa64a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f208ded97430dd502cbea8942b8cb84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c12bbd56ed49f614e5a673df2dcf7697 |
| publicationDate | 2022-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114262609-A |
| titleOfInvention | Self-flashing fluorescent dye for long-time super-resolution fluorescence imaging of lysosome and synthetic method and application thereof |
| abstract | The invention relates to self-flashing fluorescent dyes for long-time super-resolution fluorescence imaging of lysosomes, and a synthesis method and application thereof. The fluorescent dye related to the invention is in a dark state with a closed-loop structure in an aqueous solution with the pH value of more than 5.5, so that the dye exists in a small amount of fluorescent state only in an acidic lysosome, and the accurate positioning of the lysosome is achieved. In addition, the dye has reciprocating change of a fluorescence state and a dark state in a lysosome so as to achieve the self-flashing effect, realize dynamic and long-time super-resolution fluorescence imaging of the lysosome, and monitor the pH, distribution, size and the like of the lysosome. |
| priorityDate | 2020-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.