http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114258405-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a335f7d1424e0d542a9d82c6e752d2e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6432 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 |
| filingDate | 2020-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfec52898dbb96352ff8a9070f4646d1 |
| publicationDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114258405-A |
| titleOfInvention | Compositions and methods for preparing factor Xa and derivatives |
| abstract | The present disclosure relates to protein sequences that can be used to generate Factor Xa proteins and derivatives thereof. These protein sequences include a factor Xa light chain portion, a heavy chain catalytic domain portion, and a C-terminal activation peptide of the heavy chain catalytic domain portion. It was found that when an activating peptide (AP) was fused to the C-terminus of the heavy chain of the Factor Xa protein or derivative, the resulting protein could be expressed more efficiently and that the attachment of the activating peptide (AP) to the heavy chain did not affect the activity of the protein. |
| priorityDate | 2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 162.