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publicationDate 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114231560-A
titleOfInvention Construction method and application of spontaneous gastric precancerous lesion animal model
abstract The invention discloses a construction method and application of a spontaneous gastric precancerous lesion animal model, and relates to the technical field of medical treatment. The invention constructs gene knockout heterozygote animal ATP4a +/‑ The gastric precancerous lesion model can be used as an animal model of gastric precancerous lesion, can spontaneously generate lesions of the full-thickness tissue abnormal incomplete intestinal epithelization stage of gastric mucosa, can be used as an animal model of gastric precancerous lesion, and is suitable for researching and developing pathogenesis of gastric precancerous lesion and drug effect and mechanism of a new drug for resisting chronic atrophic gastritis.
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