| abstract |
The invention belongs to the technical field of traditional Chinese medicine preparation, and discloses a Jianchong Chuangyu capsule, a preparation method and an optimization method. The analytic hierarchy process is used to optimize the extraction process of the Jianchong Chuangyu capsule with multiple indexes; ; Optimize the concentration and drying process of Chichong Chuangyu Capsules. The invention determines that the extraction solvent is water, the total solvent consumption is 18 times, the extraction time is 30 minutes, and the extraction is performed twice; the ultrafiltration membrane ultrafiltration molecular interception is determined to be 100,000, the working pressure is 0.07MPa, and the material-liquid concentration ratio is 1:12. Concentration and drying process: vacuum concentration, 60°C, 0.08-0.09MPa, drying process parameters are: plate thickness 2cm, working pressure 0.09MPa, and temperature 80°C. The extraction process screening, extraction process optimization, molding process, quality standard, stability analysis and preliminary pharmacodynamic analysis of the present invention have not been reported in domestic literature. |