| abstract |
The invention provides a dry powder inhalation of fresh ginseng under the forest, a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. In the present invention, the fresh ginseng extract is prepared and the micropowder is prepared by spray drying technology, and the addition of auxiliary materials is optimized, and the auxiliary materials include any one of mannitol, glycine, L-threonine, leucine, sorbitol and lactose. one or more. Through research, it is found that the properties of micropowder prepared from different excipients are quite different. Among them, the micropowder prepared with mannitol as an excipient has the best properties. Therefore, the excipient can be selected as mannitol. , liquid mass fraction and feed volume flow, etc. to optimize. The invention successfully prepares the fresh forest ginseng dry powder inhaler, which meets the relevant requirements of the pharmacopoeia for the dry powder inhaler, and has good anti-fatigue effect and good practical application value as proved by experiments. |