http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114220484-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_795cb009fbe52eb9be778ed97897534c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20 |
| filingDate | 2021-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d20e3860cee0575dfd7e2aed64515e30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d43458894edce2c98850158cd3f4d69b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8773f60ef2e3b5f09c654b3a96d4bef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a4dc38dc2a59b3c58e261945386f38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b77174635986fe0050dc1b40675d878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf0ddeef4df3eec57fbaea6115c98f72 |
| publicationDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114220484-A |
| titleOfInvention | Identification method of individual differential expression protein |
| abstract | The invention discloses a method for identifying individual differential expression protein, which comprises the following steps: s1, preprocessing the protein abundance data; s2, verifying whether highly significant protein pairs exist in the protein abundance data of the normal queue; s3, selecting a reference group in an individual level differential expression algorithm; s4, identifying the differential expression protein by adopting an individual level differential expression algorithm based on the reference group; the method comprises the steps of preprocessing protein abundance data based on the characteristics of the protein abundance data, removing proteins with high variation coefficient and high missing value proportion, and reducing the influence of protein quantitative errors on individual difference protein results; and secondly, selecting a reference group based on the protein stability pair, continuously optimizing the proteins with differential expression in the reference group by using an iterative method, ensuring the stability of the reference group, effectively identifying the proteins with differential expression on an individual level, and having high identification precision and good application prospect. |
| priorityDate | 2021-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.