http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114213347-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-06 |
filingDate | 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114213347-B |
titleOfInvention | Bivalent ionizable lipid compound, composition and application thereof |
abstract | The invention relates to the technical field of nucleic acid drug delivery, in particular to a bivalent ionizable lipid compound, a composition and application thereof. The invention provides a plurality of ionizable cationic lipids capable of delivering nucleic acid drugs, which have stronger designability, biodegradability and high in-vivo and in-vitro transfection efficiency, and a lipid nano delivery system composed of the ionizable cationic lipids is used for delivering mRNA, is superior to products on the market at the cellular level, has good delivery efficiency at the animal level, can be used as a novel method for delivering nucleic acid drugs, and promotes the development of the nucleic acid drugs. |
priorityDate | 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.