http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114196504-A

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filingDate 2020-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8114503cefc29e0e0e4a64713217ce5f
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publicationDate 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114196504-A
titleOfInvention Exosome enrichment chip based on chitosan positive and negative charge adsorption principle and preparation method thereof
abstract An exosome enrichment chip based on a chitosan positive and negative charge adsorption principle and a preparation method thereof are disclosed, which comprises the following components: the upper layer is a straight channel liquid path layer, and the lower layer is a triangular column mixed flow liquid path layer; the device is specifically provided with the following structures: sample introduction port, sample separation zone and sample outlet. The preparation method of the exosome-enriched chip based on the chitosan positive and negative charge adsorption principle comprises the following steps: preparing a photoresist template with a raised channel part; developing and hardening; treating the template with a silylating agent; obtaining a polydimethylsiloxane chip with a structure; and (4) irreversible sealing. The invention has the advantages of simple structure, convenient preparation and operation, high speed, high efficiency and wide application range.
priorityDate 2020-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 25.