http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114195898-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 |
filingDate | 2021-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114195898-B |
titleOfInvention | Humanized anti-CD33 single domain antibody and preparation method and application thereof |
abstract | The present invention relates to an anti-CD33 humanized single-domain antibody and its construct, its preparation method and application, especially in the treatment and/or prevention or diagnosis of CD33-related diseases such as tumors. The preparation method of the humanized anti-CD33 single-domain antibody of the present invention has simple steps, and the obtained anti-CD33 humanized single-domain antibody has good affinity and specificity for CD33 protein. The CD33 chimeric antigen receptor obtained by the anti-CD33 heavy chain single-domain antibody (VHH) recombinant vector can target and attack the tumor cells expressing the CD33 antigen with high specificity, and the preparation for treating malignant tumors is prepared. |
priorityDate | 2021-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 673.