http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114181077-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06b3ec97161bea8b62d865ea3ffe5b71 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-757 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08 |
| filingDate | 2021-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd6337c0a08b9bbebfeb313133bde1b8 |
| publicationDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114181077-A |
| titleOfInvention | Method for synthesizing tranexamic acid |
| abstract | The invention discloses a synthetic process of tranexamic acid (I), which comprises the following steps: taking 3-cyclohexene formate (V) as a raw material, and obtaining an intermediate 3-cyclohexene formate (IV) through an esterification reaction; the Intermediate (IV) and carbon monoxide/hydrogen mixed gas or synthesis gas are subjected to carbonyl insertion reaction in the presence of a catalyst to obtain an intermediate 4-formylcyclohexane-1-formate (III) with high selectivity; inThe intermediate (III) is subjected to reductive amination to obtain an intermediate 4-aminomethyl cyclohexanecarboxylate (II); finally hydrolyzing and transforming the intermediate (II) to obtain the tranexamic acid (I). The method has the advantages of cheap and easily-obtained raw materials, environment-friendly carbon monoxide carbonyl insertion reaction, simple and efficient route and provides a new method for synthesizing tranexamic acid (I). |
| priorityDate | 2021-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 149.