http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114163323-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46be9cc10f2d5a5a9f7329fa96b45251 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-373 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-02 |
| filingDate | 2021-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14354c43d7ef621d99941bf3c8deafd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa50a17bd765c8f038c5eff33c91f16b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42655321a4ead7bfd35e71525a2ad44c |
| publicationDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114163323-A |
| titleOfInvention | Synthetic method of 3-oxocyclobutanecarboxylic acid |
| abstract | The invention discloses a synthesis method of 3-oxocyclobutanecarboxylic acid, belonging to the technical field of organic chemistry. 2-acyl-1, 3-dibromopropanol and diisopropyl malonate are used as starting materials, and are reacted in a polar aprotic solvent under the action of alkali, an activating agent and a phase transfer catalyst, and inorganic base is hydrolyzed to generate a compound I; then, under the condition of sodium hypochlorite and alkaline, 2,2,6, 6-tetramethyl piperidine oxide is catalyzed and reacted to generate a compound II; finally deacidifying under the action of pyridine, 4-dimethylaminopyridine and lithium chloride to generate the 3-oxocyclobutanecarboxylic acid. The method has the characteristics of simple and convenient reaction operation and high yield, and has the potential of industrial amplification. |
| priorityDate | 2021-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.