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filingDate 2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114163230-B
titleOfInvention A kind of calcium phosphate bioceramic with ultra-fine uniform grain and preparation method thereof
abstract The invention discloses a calcium phosphate bioceramic with ultra-fine and uniform crystal grains and a preparation method thereof, belonging to the technical field of biomedical materials and solving the problem of poor mechanical properties of the calcium phosphate bioceramic in the prior art. The preparation method of calcium phosphate bioceramic with ultra-fine and uniform crystal grains of the present invention comprises the following steps: pre-sintering calcium phosphate initial powder at low temperature to form a primary crystal phase; subjecting the pre-sintered calcium phosphate powder to wet ball milling, and then Gradient centrifugation of the slurry after ball milling to separate calcium phosphate powder with small grain size and narrow distribution; the calcium phosphate powder obtained after ball milling and centrifugation is made into a ceramic green body; the ceramic green body is sintered in two steps, and the second After the first step of sintering and heat preservation, quenching and rapid cooling are performed immediately to obtain calcium phosphate bioceramics. The calcium phosphate ceramics prepared by the method of the invention have uniform grain size, not only have excellent mechanical properties, but also have better biological activity, and meet the requirements for repairing clinical load-bearing bone defects.
priorityDate 2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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