http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114149991-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6aa6e7ff51825ce9920759e4f8e2ce0e |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
filingDate | 2021-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d1f450a9286db302beb77b5d68c06b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_367fb7ba6835ef713463359d327f15be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0191838b475edeac8e0e9506754974f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d1bbfd51b58c6ec69cf0d5e7c542434 |
publicationDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114149991-A |
titleOfInvention | A kind of siRNA of GILZ gene and its application |
abstract | The invention discloses a GILZ gene siRNA and its application, and belongs to the technical field of biomedicine. The present invention provides small interfering RNA for the GILZ gene that is underexpressed in lung cancer cells. Relevant cytological experiments show that the small interfering RNA provided by the present invention has important functions of inhibiting the protein expression of GILZ in lung cancer cells and promoting the survival, proliferation and invasion of cancer cells. Therefore, the siRNA molecule targeting the GILZ gene provided by the present invention can be used to establish a growth-related model of lung cancer cells, which is helpful to clarify the role of the GILZ gene and its target genes, and to clarify the development law of the GILZ transcription factor in malignant tumors. To provide help for the study of the pathogenesis of lung cancer from the molecular level. |
priorityDate | 2021-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 219.