| abstract |
The invention discloses a bionic hydrogel for regulating and controlling bone and chondrocyte to promote repair, which comprises an upper cartilage layer and a lower bone layer, wherein the cartilage layer comprises polyglutamic acid, carboxymethyl chitosan, bacterial cellulose, magnesium sulfate, water, N-hydroxysuccinimide and 1- (3-dimethylaminopropyl) -3-ethyl carbodiimide hydrochloride; the bone layer comprises polyglutamic acid, carboxymethyl chitosan, bacterial cellulose, copper sulfate, water, N-hydroxysuccinimide and 1- (3-dimethylaminopropyl) -3-ethyl carbodiimide hydrochloride; the interface between the cartilage layer and the bone layer is tightly connected. Also discloses a preparation method of the bionic hydrogel for regulating and controlling bone and cartilage cells to promote repair. |