http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114134151-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9bcdb3cee33de132012223880721c77 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y502-01008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate | 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_091800fed998d575cff5c22c3670f8b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dc620813eed4d09067cac6aee2e5d97 |
publicationDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114134151-A |
titleOfInvention | Small interfering nucleotide duplex for treating hypertrophic scar and scar and its application |
abstract | The invention belongs to the technical field of biomedicine, and discloses the application of FKBP10 as a therapeutic target of hypertrophic scar. The invention also discloses a small interfering nucleotide duplex for treating hypertrophic scars and scars, and the small interfering nucleotide duplex is designed by using FKBP10 as a target. The present invention further discloses a medicine for treating hypertrophic scar, which at least comprises a small interfering nucleotide duplex designed with FKBP10 as a target. The present invention discloses a method for treating hypertrophic scar, comprising the following steps: taking FKBP10 as a target, designing a double-stranded small interfering nucleotide; selecting the most effective siRNA from it; modifying the selected siRNA or preparing it with a carrier Nanoparticle formulation; subcutaneous or intradermal injection for the treatment of hypertrophic scars. The siRNA designed with FKBP10 as the target of the present invention will become a specific drug for treating hypertrophic scars and scars after being modified or forming nanoparticles with a carrier, and has a broad application market. |
priorityDate | 2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 178.