Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_267030f08c9c7810eb398b8faec97751 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b51887aa6a703326fc2858d38e09483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bc3988ce4dcd4f5753e72293e899deb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_340aaa307da896a8ddf020ecdb3c42be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66b1463a6b5fab520f4272b80912e023 |
publicationDate |
2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114134147-A |
titleOfInvention |
A non-coding RNA regulating FZD9 and its application |
abstract |
The invention belongs to the technical field of genetic engineering, and relates to a non-coding RNA for regulating FZD9 and its application. The non-coding RNA for regulating FZD9 is named lncRNA MSTRG.24062.2, and the nucleotide sequence of its coding region is shown in SEQ ID NO.1 It is shown that the non-coding RNA can regulate the target gene FZD9 by combining with miRNA-125a-5p or miRNA-125b-5p, thereby significantly regulating the osteogenic differentiation of bone marrow mesenchymal stem cells and implant-osseointegration; the present invention is the first time The functional characterization of lncRNAMSTRG.24062.2 confirmed the potential value of lncRNA as a bone biomarker, and provided a new way to further study osteoporosis and the clinical diagnosis and treatment of related patients. |
priorityDate |
2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |