http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114129773-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf235e4b3dc28f2153f20c6bd3624c3b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34 |
| filingDate | 2021-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f22f1fcd4d899a6c695db62906b9c510 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44e15ed7768c992c0fa4cf1a857df704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_769c72ca551f3cf28743f9c2e9a840ee |
| publicationDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114129773-A |
| titleOfInvention | A titanium implant with osteopromoting and antibacterial properties on the surface and preparation method thereof |
| abstract | The elderly have a high incidence of osteoporosis, and the commonly used bone implants lack osseointegration, which can easily lead to loosening and infection. The invention finds that the antibacterial drug mecillin has an osteopromoting effect through computer screening combined with cell and animal experiments, and loading it on the surface of a bone implant can prepare a drug-carrying bone implant with both osteopromoting and antibacterial effects. The invention also discloses the preparation method of the above-mentioned drug-loaded bone implant, which includes the following steps: 1) pretreating the bone implant matrix to obtain the surface topography of the micro-nano structure on its surface; 2) implanting the bone implant After the pretreatment of the body matrix, the bone implant is exposed to the dopamine solution for a period of time to form a polydopamine coating on its surface, and then the bone implant is contacted with a solution containing mecillin, using the excellent polydopamine layer on the surface of the bone implant. 3) Rinse the material with deionized water and dry it naturally. |
| priorityDate | 2021-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.