abstract |
The present invention relates to compositions and methods related to particle removal. The present invention provides scavenging particles, methods for treating subjects with cancer, autoimmune diseases, neurodegenerative diseases, methods for promoting healthy aging in subjects, methods for treating metabolic disorders in subjects Methods of disorders and methods for increasing muscle mass in a subject. Among other things, the present disclosure provides compositions and pharmaceutical compositions thereof that bind to and inhibit the biological activity of soluble biomolecules. The composition may include a plurality of particles that specifically bind to a target (eg, a soluble biomolecule or biomolecules on the surface of a pathogen) to inhibit the target (or pathogen) from interacting with other molecules or cells. The present disclosure also provides applications (eg, therapeutic applications) in which the compositions are useful. |