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filingDate 2021-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e098e5242c0ef43217e39211e314230
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publicationDate 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114113437-A
titleOfInvention HPLC (high Performance liquid chromatography) fingerprint of heat-clearing and detoxifying oral liquid and application of HPLC fingerprint in quality control of heat-clearing and detoxifying oral liquid
abstract The invention discloses an HPLC (high performance liquid chromatography) fingerprint of heat-clearing and detoxifying oral liquid and application thereof in quality control of the heat-clearing and detoxifying oral liquid, wherein the HPLC fingerprint is constructed on the basis of the following chromatographic conditions: the liquid chromatograph is a Waterse2695 high performance liquid chromatograph; the chromatographic column is Sapphire C18 with specification of 4.6mm × 250mm and 5 μm; the mobile phase is methanol-0.2% phosphoric acid water solution, gradient elution is carried out, the flow rate is 1ml/min, the column temperature is 35 ℃, the detection wavelength is 238nm, and the number of theoretical plates is not lower than 6000 according to the calculation of baicalin peak. The HPLC fingerprint of the heat-clearing and detoxifying oral liquid provided by the invention can be effectively used for controlling the quality of the heat-clearing and detoxifying oral liquid, and can overcome the defect that the traditional quality control method is difficult to comprehensively, objectively, accurately and efficiently evaluate the quality of the heat-clearing and detoxifying oral liquid.
priorityDate 2021-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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