| abstract |
The invention discloses HAp-SF artificial periosteum loaded with SDF-1α/CGRP and a preparation method thereof, belonging to the field of orthopedic implant materials. The method of silk to prepare nHA/SF absorbable artificial periosteum loaded with SDF-1-α and CGPR factors, the prepared artificial periosteum has the performance of loading and slow-releasing SDF-1-α and CGPR factors, so that it has good osteogenesis Angiogenesis and biocompatibility. In addition, the invention can play a barrier function in the local defect, and can effectively prevent the ingrowth of surrounding soft tissue and the occurrence of heterotopic ossification. The artificial periosteum also has good mechanical strength and biodegradability, and can be used as a repair material for bone tissue defects. use. |