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filingDate 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114099441-A
titleOfInvention A kind of chlortetracycline hydrochloride dry suspension and its preparation method and application
abstract The invention relates to a dry suspension of chlortetracycline hydrochloride and a preparation method and application thereof. The dry suspension of chlortetracycline hydrochloride comprises the following raw materials in terms of mass percentage: 15-35% of chlortetracycline hydrochloride, a suspending agent 1 ~ 15%, pH adjuster 1 ~ 5%, flavoring agent 0.1 ~ 1% and filler 44.9 ~ 82.9%. The method includes the following steps: S1. crushing chlortetracycline hydrochloride and sieving; S2. sieving the remaining auxiliary materials; S3. weighing chlortetracycline hydrochloride, suspending agent, pH value adjusting agent and vacuum for flavoring agent according to the proportions Load the material into a stirring tank, add an appropriate amount of purified water to form a suspension; S4. Spray dry the suspension and pass it through an 80-mesh sieve; S5. Mix the product obtained by spraying and the filler in a mixer evenly, that is, Chlortetracycline hydrochloride dry suspension. The product of the invention is acidic, can be used in combination with the synergistic drug of chlortetracycline hydrochloride, and the aqueous solution has good palatability. The clinical test results show that the product of the invention improves the clinical effect and blood concentration of chlortetracycline hydrochloride.
priorityDate 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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