http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114085317-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F2-38
filingDate 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2023-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2023-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114085317-B
titleOfInvention A kind of reactive UCST copolymer and preparation method thereof
abstract The invention discloses a reactive UCST copolymer and a preparation method thereof, belonging to the technical field of temperature-sensitive polymers. The side chain structure of the copolymer of the present invention includes: acrylamide monomers and reactive monomers, wherein the molar ratio of acrylamide monomers to reactive monomers is 1.7:1-20:1. The UCST property of the copolymer is reflected in that it can undergo a reversible phase transition in which it is insoluble in low temperature and soluble in high temperature, and the phase transition temperature is 15-90°C; Or the covalent reaction of polymers can co-assemble with proteins to form polymer-protein nanoparticles, and the proteins can maintain the original secondary structure and biological activity during the co-assembly process. The reactive UCST copolymers in nano Delivery, biosensors, and molecular purification and enrichment all have potential applications.
priorityDate 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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