http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114085261-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ec105ea6a151157ba165830e5a8583 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2fb25dee51f7544c9abd4424e7153fd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-002 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_196cdac361e127f394509d14d56bd5f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11a97e305511839d30523511bbee3f83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfa9ab1ad3baec00f6bf30574e761ddb |
| publicationDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114085261-A |
| titleOfInvention | A kind of preparation method of benzoprogesterone and intermediate thereof |
| abstract | The invention belongs to the technical field of preparation of steroid hormone drugs, and in particular relates to a preparation method of benzoprogesterone, comprising using 4-AD as a starting material, and obtaining through acetylene reaction, catalytic hydration reaction, oxidation reaction and ketal reaction to obtain The target product, benzoprogesterone, wherein the catalytic hydration reaction is the catalytic hydration reaction of an acetylenic reactant and a copper salt under the catalysis of an acid, and the reaction is carried out at 25-55° C. for 3-5 hours to obtain a catalytic hydrate. Compared with the existing process route, the invention has the advantages of cheap and easy-to-obtain raw materials, and can avoid the use of highly toxic reagents such as osmium tetroxide, acetone cyanohydrin and the like. |
| priorityDate | 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.