| abstract |
The invention discloses a preparation method and application of an angelica sinensis extract, wherein the preparation method comprises the following steps: s1, preparing an angelica oil extract: ultrasonically extracting angelica by using an acidic ethanol aqueous solution with the volume fraction of 80-90%, centrifuging, and collecting an oil phase and a water phase, wherein the oil phase is an angelica oil extract; s2, performing alumina column chromatography on the water phase prepared in the step S1, and sequentially eluting with water, ethanol aqueous solution and 70-80% by volume of acidic ethanol aqueous solution; collecting ferulic acid solution and chlorogenic acid solution; and respectively carrying out reduced pressure concentration on the ferulic acid eluate and the chlorogenic acid eluate, and crystallizing to obtain a chlorogenic acid extract and a ferulic acid extract. The method can be used for simultaneously preparing high-content ferulic acid and chlorogenic acid, comprehensively utilizing the effective components in the angelica, realizing industrial production, and having safe and reliable process and environmental friendliness. |