abstract |
The present invention provides an affinity body targeting HER2 and its application. The structure of the HER2-targeting affinity body RESCA-HER2-BCH is RESCA-(AEEA)-VDNKFNKEMRNAYWEIALLPNLNNQQKRAFIRSLYDDPSQSANLLAEAKKLNDAQAPK[(Acp)-(Acp)]. Through the diagnostic and therapeutic radionuclide labeling and evaluation of RESCA‑HER2‑BCH, it is expected to be used for the diagnosis and treatment of HER2 positive tumors such as HER2 positive breast cancer, gastric cancer, cervical cancer, prostate cancer, and lung cancer. |