| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18f4b13b863327ab144da2ed26a333a1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-367 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-689 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate |
2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd17af4d08bab1b980a1b77ad945c32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_235d42dbae2a5401650ee40f5cf2fdeb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbf2b325652951911c24175cb3fcc9ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f01dda1a12f9a00dc8f8e0dfa7a49b83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4a0ac41e7802b72b101ae74bbba7093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a918ad81169121167f30b0020d888167 |
| publicationDate |
2022-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114062687-A |
| titleOfInvention |
Biomarker related to non-obstructive azoospermia and application thereof |
| abstract |
The invention discloses a biomarker related to non-obstructive azoospermia and application thereof. The biomarker includes SHISA5 protein. The invention discovers for the first time that the concentration of Wnt receptor inhibitor protein SHISA5 in the semen of an NOA patient is obviously lower than that of a normal male, and provides that the SHISA5 protein can be used as a potential early warning molecule for evaluating the spermatogenic dysfunction of the NOA patient, which is helpful for expanding and diagnosing NOA indexes to enlarge the diagnosis range and has important significance for the NOA diagnosis field. |
| priorityDate |
2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |