| abstract |
The invention relates to the fields of immunology technology, biotechnology and biomedicine, in particular to a vaccine for preventing novel coronavirus pneumonia COVID-19 and a preparation method thereof. A composition of immunogenic conjugates includes at least two combinations of immunogenic conjugates comprising the same carrier protein or at least two combinations of immunogenic conjugates comprising 2 different carrier proteins. The immunogenic conjugate composition is used for preparing a vaccine for preventing COVID-19. Compared with the traditional attenuated vaccine, inactivated vaccine and other novel vaccines, the vaccine can quickly cope with virus variation; the site requirement required by vaccine production is reduced, and large-scale batch production is facilitated; the research and development cost and the research and development period are reduced; safe, nontoxic and stable; due to the small and simple molecular structure, serious complications and iatrogenic infection problems are rarely caused. |