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filingDate 2021-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9358531a6fb1ef262a1a5698a8fb4047
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publicationDate 2022-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114053287-A
titleOfInvention Application of aspirin in the preparation of medicine for preventing and treating unexplained recurrent miscarriage
abstract The invention relates to the application of aspirin in the preparation of a medicine for preventing and treating unexplained recurrent miscarriage. The invention adds a small dose of aspirin to the drinking water of the unexplained recurrent abortion mice, which not only reduces the embryo absorption rate, but also improves the inflammatory response of the mouse decidual tissue, and reduces the HMGB1 of the mouse serum and decidual tissue. high levels of HMGB1 in mice with unexplained recurrent miscarriage can further trigger pro-inflammatory responses, thereby effectively protecting and treating the pregnancy rate in mice with unexplained recurrent miscarriage.
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