http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114051974-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d496576561159f683d5fd7c887538114 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate | 2021-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3630282cef250d9933121e80e2abdbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52a537172049b635bff259f5acbf56bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b99fc4743a6ac915761702b0d6909dea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_395058e07f638197f18c71223d2148ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83161c3c281f19433527bb2f16809b88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81354cb3b4dbf1b5022a2307d4e1b313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f7340071da178f8e326fb34f62eff01 |
| publicationDate | 2022-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114051974-A |
| titleOfInvention | A liver cancer model and its construction method and application |
| abstract | The invention relates to the technical field of biological models, in particular to a construction method and application of a liver cancer tumor model. Mice were fed with a high methionine diet with a methionine content of 2% until the modeling was successful; from the first week, CCl 4 was administered by gavage twice a week until the modeling was successful; from the first week, DEN was injected intraperitoneally, The injection was performed once a week for 4 consecutive weeks; the modeling time was 8 weeks. The present invention uses high methionine feed combined with diethylnitrosamine (DEN) and carbon tetrachloride (CCl 4 ) to construct a liver cancer tumor model for the first time. The operation is simple, the cycle is short (8 weeks), and the success rate is high (tumor formation rate of 93 %) with a low mortality rate. It has the irreplaceable necessity of other models and has broad research and application prospects. |
| priorityDate | 2021-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.