http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114047280-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8809 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate | 2021-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114047280-B |
| titleOfInvention | A kind of detection method of non-volatile unknown substance content in medical device extract |
| abstract | The invention discloses a method for detecting the content of non-volatile unknowns in an extract of medical equipment, comprising the following steps: first, preparing a mixed solution of an antioxidant 1098 series standard solution and a substitute standard product, and using liquid chromatography-mass spectrometry combined with The solution prepared by the instrument is tested, and the calibration curve of antioxidant 1098 is established according to the test results and the relative response factor of the surrogate standard relative to the antioxidant 1098 is calculated; secondly, the medical device is leached, and the leaching solution is obtained, using the liquid phase Chromatography-mass spectrometry was used to detect the extract, and the results of the extract were compared and identified with the results of antioxidant 1098 and the mixed solution of substitute standard products, and the concentration of unknown substances in the extract was calculated; finally , and calculate the unknown content according to the unknown concentration. The detection method provided by the invention reduces the safety risk brought by only focusing on the quantitative results of the known nonvolatile substances, and also reduces the cost of developing and verifying a variety of known nonvolatile substances. |
| priorityDate | 2021-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.