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filingDate 2021-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114045257-A
titleOfInvention Vascularized osteoblast membrane scaffold complex and preparation thereof
abstract The invention provides a vascularized osteoblast membrane scaffold complex and a preparation method thereof, wherein a method for co-culturing osteoblasts and angiogenic cells is adopted, the loss of extracellular matrix caused by the traditional cell digestion technology is eliminated through a cell membrane technology, the original cell microenvironment is reserved, and the survival and the return of osteoblasts in a bone tissue engineering scaffold are facilitated through the synergistic effect of osteogenesis and angiogenesis; furthermore, the organic combination of the 3D printing bone tissue engineering scaffold and the cell membrane solves the problems that the strength of a pure cell membrane is low and an osteogenic space cannot be maintained.
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