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filingDate 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114045045-B
titleOfInvention A class of single-photon up-conversion pentamethyl tetracyanine photosensitive dyes, preparation method and application thereof
abstract The present invention provides a class of single-photon up-conversion pentamethine cyanine photosensitive dyes, a preparation method and applications thereof, and the photosensitive dyes have the structure of general formula I. The pentamethine cyanine-based photosensitizing dye without heavy atom modification and having single-photon up-conversion property of the present invention has a high singlet oxygen generation ability under the light excitation longer than its own maximum absorption wavelength. Under the excitation of upconverted light, it can effectively photodynamically kill cancer cells in deep tissues, and can be used for photodynamic therapy of solid tumors in vivo, and has a good application prospect for inhibiting the growth of deep tumors.
priorityDate 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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