http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114031553-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a66522c35be4f3ac56dd89788416d534 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 |
filingDate | 2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25b9bb321f58417c73ad276bbb696a9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9123ddcd588a219ca0d961410174ff7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf90ac3ffc9ed6e2c7fefeb93da2760d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_972ae869eac2af03c8f9c9cb72111914 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4adee6785b45b2aa693703b6e8d1a8a1 |
publicationDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114031553-A |
titleOfInvention | Preparation method of 4- [ (methoxyacyl) methyl ] -3, 4-dihydroisoquinoline-1 (2H) -ketone compound |
abstract | The invention takes cheap N-alkyl-N- [ (2-methyl) allyl ] aryl formamide as a raw material, takes chemical methyl formate as a carbon 1 source instead of carbon monoxide, takes tert-butyl peroxyacetate as a free radical initiator, and synthesizes a series of 4- [ (methoxyacyl) methyl ] -3, 4-dihydroisoquinolinone compounds through a carbon-hydrogen free radical cascade cyclization reaction. The method has the advantages of simple operation, cheap raw materials and wide application range of the substrate, synthesizes 3, 4-dihydroisoquinolinone compounds with diversified structures, enriches the types of the 3, 4-dihydroisoquinolinone compounds and provides a choice for seeking medicinal active molecules. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115260096-A |
priorityDate | 2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.