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filingDate 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_396d603324f2de504ee7c6739117ee1c
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publicationDate 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114028572-A
titleOfInvention New application of MAT2A inhibitors for the treatment of asthma
abstract The present invention provides a new application of MAT2A inhibitor for treating asthma. Specifically, the present invention provides the use of a MAT2A inhibitor in the preparation of a medicament for the treatment of asthma or its related diseases. The present invention also provides the use of a MAT2A inhibitor in the preparation of a preparation for inhibiting the biosynthesis of the universal methyl donor S-adenosylmethionine to inhibit the function of type 2 native lymphoid cells. The present invention also provides the use of a MAT2A inhibitor in the preparation of a preparation for inhibiting the function of type 2 innate lymphoid cells; preferably, the inhibiting the function of type 2 innate lymphoid cells comprises inhibiting or reducing type 2 innate lymphoid cells Cellular type 2 cytokine expression. The present invention also provides the application of targeting the methionine cycle in screening and/or preparing medicines for the treatment of asthma or its related diseases.
priorityDate 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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